William A. Howard

Research Description

Research in my laboratory is focused on synthetic and mechanistic transition metal chemistry. My research interests include (1) creating transition metal — based drugs for treating the symptoms of malignant diseases, and (2) rigorously studying the chemical behavior of a particular transition metal in order to understand better the general principles governing the outcomes of chemical reactions. This work often requires the use of an inert atmosphere glovebox, a high vacuum line, and Schlenk techniques.

Currently there are two research projects based on these interests that are ongoing in my lab. The first project involves preparing and characterizing new vanadium complexes and testing selected samples as insulin mimics. The second project involves preparing and characterizing new rhodium complexes in order to learn more of the coordination chemistry of this metal.

Selected Publications
  1. “Aqueous Acid – Base Chemistry Involving Dioxovanadium(V) Complexes of 2,6-Pyridinedimethanol, and the X-Ray Structures of Na[VO2{2,6-(OCH2)2NC5H3}] · 4 H2O and [1-H-2,6-(HOCH2)2NC5H3]Cl.”  Fites, Raena J.; Yeager, Adam T.; Sarvela, T. L.; Howard, William A.; Zhu, Guang; Pang, Keliang  Inorg. Chim. Acta 2006, 359, 248-56.
  2. “The Relationship between Balancing Reactions and Reaction Lifetimes:  A Consideration of the Potassium-Argon Radiometric Method for Dating Minerals.”  Howard, William A.  J. Chem. Educ.2005, 82, 1094-98.
  3. “Syntheses and Characterization of Some Chloro, Methoxy, and Mercapto Derivatives of [Ru( h 2-2,2’-bipyridine)3]2+ 2 PF6-:  Crystal and Molecular Structures of [Ru( h 2-2,2’-bipyridine)2( h 2-4,4’-(X)2-2,2’-bipyridine)]2+ 2 PF6- (X = Cl, OCH3).”  Hansen, Lars E.; Glowacki, Emily R.; Arnold, Danielle L.; Chi, Bongchu; Bernt, George J.; Fites, Raena J.; Freeburg, Ruth A.; Rothschild, Roger F. N.; Krieg, Maggie C.; Howard, William A.; Tanski, Joseph M. Inorg. Chim. Acta2003, 348, 91-96.
  • B.S. 1990, Tulane University (Chemistry)
  • M. Phil. 1994 Columbia University (Inorganic Chemistry)
  • Ph.D. 1995, Columbia University (Inorganic Chemistry)

phone: 907.474.6019
fax:
907.474.5640
email:
wahoward@alaska.edu
address:

William A. Howard
Department of Chemistry & Biochemistry
University of Alaska Fairbanks
Fairbanks, AK 99775-6160

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