Research Description
My research focuses on development of bioanalytical methods. We are developing robust capillary electrophoresis methods for the analysis for neurotransmitters/neuromodulators, with a special emphasis on fluorescence detection of D-amino acids and adenosine in the mammalian brain. Our group is also involved in the synthesis of modified "single isomer" cyclodextrins as novel chiral selectors in capillary electrophoresis. Finally, we are collaborating with biologists in the analysis of secondary metabolites in Alaska/Norwegian lichens, especially in relation to microbial degradation of the metabolites in the rumen of reindeer and caribou.
Selected Publications
- Kirschner, D. L.; Jaramillo, M.; Green, T. K. "Enantioseparation and Stacking of Cyanobenz[f]isoindole-Amino Acids by Reverse Polarity Capillary Electrophoresis and Sulfated beta-Cyclodextrin." Analytical Chemistry 2007, 79(2), 736-743.Abstract
- Falk, A.; Green, T. K.; Barboza, P "Quantitative determination of secondary metabolites in Cladina stellaris and other lichens by micellar electrokinetic chromatography." Journal of Chromatography A, 2008, 1182(1), 141-144.
- D. Kirschner, M. Jaramillo, T. Green, F. Hapiot, L. Leclercq, H. Bricout, E. Monflier,"Fine tuning of sulfoalkylated cyclodextrin structures to improve their mass-transfer properties in an aqueous biphasic hydroformylation reaction" Journal of Molecular Catalysis A: Chemical 2008, 286, 11-20.
- D. L. Kirschner, T. K. Green, "Separation and sensitive detection of D-amino acids in biological matrices" Journal of Separation Science 2009, 32, 2305-2318.
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- B.S. 1977, Kearney State College
- Ph.D. 1984, University of Tennessee
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phone: 907.474.1559
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fax: 907.474.5640
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email: fftkg@uaf.edu
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address:
Thomas K. Green
Department of Chemistry & Biochemistry
University of Alaska Fairbanks
Fairbanks, AK 99775-6160
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