Research in the Drew lab focuses on three aspects of hibernation biology. The first involves mechanisms of intrinsic neuroprotective properties of Arctic ground squirrel brain in the hibernating and euthermic state. The second involves mechanisms and cognitive significance of synaptic remodeling observed during hibernation torpor and arousal. The third involves central nervous system regulation of metabolic suppression in hibernation.

1. Weltzin MM, Zhao HW, Drew KL, Bucci D Arousal from Hibernation Alters Contextual Learning and Memory. Behavioral Brain Research, 2005 Oct 7; [Epub ahead of print]
2. Ross AP, Christian SL, Zhao HW and Drew KL, Persistent tolerance to oxygen and nutrient deprivation and N-methyl-D-aspartate in cultured hippocampal slices from hibernating Arctic ground squirrel. J. Cerebral Blood Flow and Metabolism, 2006 Jan 4; [Epub ahead of print]
3. Dave KR, Prado R, Raval AP, Drew KL, Perez-Pinzon MA, The Arctic ground squirrel brain is resistant to injury from cardiac arrest during euthermia, Stroke, 37(5):1261-5.
4. Zhao H, Ross AP, Christian SL, Buchholz JN, Drew KL,. 2006, Decreased NR1 phosphorylation and decreased NMDAR function in hibernating Arctic ground squirrels. J. Neurosci. Res., 84(2), 291-298.
5. Ross AP, Drew KL, 2006, Potential for discovery of neuroprotective factors in serum and Tissue Isolated from Hibernating Species. Mini Reviews in Medicinal Chemistry, 6, 875-884.