Read: DNA Detectives , DNA Fingerprinting lab (in lab book)

And The RNA message is sometimes edited

DNA Fingerprinting

1. Know that the sequence of base pairs (on homologous chromosomes) differ about every 200-500 base pairs. (This is known as genetic polymorphism).
2. Know that a restriction site is where an enzyme (called a restriction endonuclease) hydrolyzes DNA.
3. Restriction endonucleases cut DNA at very specific sites.
4. Be able to explain why a restriction endonuclease might cut one person's DNA into 3 strands and another person's DNA into only 2 strands.
5. Explain what a restriction enzyme digest is and what is meant by Restriction Fragment Length Polymorphisms (RFLPs).
6. Be able to interpret the results of a restriction digest.

Preview a procedure similar to your fingerprinting lab

Apoptosis

1. Recognize 2 processes for cell death (necrosis and apoptosis).
2. Know that the protein p53 detects DNA damage and initiates cell suicide (apoptosis). (The gene that codes for the p53 protein is called the p53 gene. Because p53 initiates cell suicide, the p53 gene is a tumor-suppressor gene).
3. Know that the protein bcl-2 stops p53 from initiating cell suicide.
4. Tumors contain lots of bcl-2 protein suggesting that inhibition of cell suicide may lead to cancer.

The cell cycle

The DNA Learning Center (Click on Concept 19)

Discovering that RNA is an Intermediary Between DNA and Protein

Sequencing DNA