The five-story William O’Neill Resources Building opened in 1973 and houses the School of Fisheries and Ocean Sciences as well as labs and offices for the School of Natural Resources and Agricultural Sciences.

William O'Neill was a 1934 graduate of the Alaska Agricultural College and School of Mines and a member of the University of Alaska Board of Regents for 25 years, serving as president from 1970 to 1974. The University of Alaska Alumni Association honored him as Alumnus of the Year in 1968.